Frequency and morphological study of testicular germ cell tumor.

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چکیده

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Primordial Germ Cell ; TGCT , Testicular Germ Cell Tumor ; SNV , Single Nucleotide Variant ; BAF , B - Allele Frequency

Adult male germline stem cells (spermatogonia) proliferate by mitosis and, after puberty, generate spermatocytes that undertake meiosis to produce haploid spermatozoa. Germ cells are under evolutionary constraint to curtail mutations and maintain genome integrity. Despite constant turnover, spermatogonia very rarely form tumors, so-called spermatocytic tumors (SpT). In line with the previous id...

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Primordial Germ Cell ; TGCT , Testicular Germ Cell Tumor ; SNV , Single Nucleotide Variant ; BAF , B - Allele Frequency ; GCNIS , Germ Cell Neoplasia

Adult male germline stem cells (spermatogonia) proliferate by mitosis and, after puberty, generate spermatocytes that undertake meiosis to produce haploid spermatozoa. Germ cells are under evolutionary constraint to curtail mutations and maintain genome integrity. Despite constant turnover, spermatogonia very rarely form tumors, so-called spermatocytic tumors (SpT). In line with the previous id...

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Germ Cell ; TGCT , Testicular Germ Cell Tumor ; SNV , Single Nucleotide Variant ; BAF , B - Allele Frequency ; GCNIS , Germ Cell Neoplasia In

Adult male germline stem cells (spermatogonia) proliferate by mitosis and, after puberty, generate spermatocytes that undertake meiosis to produce haploid spermatozoa. Germ cells are under evolutionary constraint to curtail mutations and maintain genome integrity. Despite constant turnover, spermatogonia very rarely form tumors, so-called spermatocytic tumors (SpT). In line with the previous id...

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Giant Testicular Mixed Germ Cell Tumor

Objective: We report a case that we believe to be the largest example of a testicular mixed germ cell tumor with a clearly defined histology pattern. Clinical Presentation and Interventions: A 21-year-old patient consulted a urologist concerning a giant testicular mass. At the time of presentation the tumor measured 29 ! 20 ! 16 cm, with a weight of 4,850 g. Serum ·-fetoprotein was over 15,000 ...

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Histopathology and Biology of Testicular Germ Cell Tumor

The versatile histopathology, clinical presentation, and biologic behavior of testicular neoplasms reflect the complex composition of the male gonad. Each component can develop different tumor types; thus, there are testicular germ cell tumor (TGT), sex cord/stromal tumor, miscellaneous tumors arising from rete testis or paratesticular structures, and tumors not specific to testicular parenchym...

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ژورنال

عنوان ژورنال: The Professional Medical Journal

سال: 2019

ISSN: 2071-7733,1024-8919

DOI: 10.29309/tpmj/2019.26.10.4144